The positions are available for highly motivated and skilled individuals with expertise in next generation sequencing (NGS) analysis and statistical genomics. Dr. Kong’s group in the Computational Health Informatics Program at Boston Children’s Hospital, Boston, MA, USA are looking for enthusiastic and talented genome scientists at various levels (post-docs and research scientists). We seek to improve current clinical practices by providing expertise and insight from large-­scale and multi­dimensional analysis of multi-­omics datasets from patients with diverse disorders.

PRIMARY DUTIES AND RESPONSIBILITIES:

  • ­  Develop novel computational and bioinformatic tools for genomic analysis.
  • ­  Statistical analysis of genomic and clinical datasets from case­-control and cohort studies and interpret the results accordingly.
  • ­  Work independently on multiple ongoing projects with flexibility to adjust to new priorities.
  • ­  Cross­-training bioinformatic colleagues.
  • ­  Present the work in form of scientific publications and oral communications to the scientific community.

The group is located at the Boston Children’s Hospital, a teaching hospital affiliated with Harvard University. 

Qualifications
  • ­Strong proficiency with R, python and other programming languages.
  • ­Familiarity with modern statistical analysis paradigms with high-­dimensional data is required.
  • ­Strong communication skills and ability to effectively translate scientific concepts to multidisciplinary personnel.
  • Demonstrated ability developing analysis schemes for whole­-genome sequencing (WGS), RNA­-Seq and epigenomic profiles.
  • Deep understanding of genomics and molecular biology.
  • Highly proficient in spoken and written English and scientific writing skills.

The candidates for post-docs or research scientists must hold a Ph.D. or equivalent degree by the start of employment.

How to apply

Interested applicants should send a cover letter outlining research experience and interests, curriculum vitae (CV), and the names and contacts of three referees to Dr. Sek Won Kong (sekwon.kong@childrens.harvard.edu).

Publications

Geisler BP, Zahabi L, Lang AE, Eastwood N, Tennant E, Lukic L, Sharon E, Chuang HH, Kang CB, Clayton-Johnson K, Aljaberi A, Yu H, Bui C, Le Mau T, Li WC, Teodorescu D, Hinske LC, Sun DL, Manian FA, Dunn AG. Repurposing existing medications for coronavirus disease 2019: protocol for a rapid and living systematic review. Systematic reviews 2021.

Börcsök J, Diossy M, Sztupinski Z, Prosz A, Tisza V, Spisak S, Rusz O, Stormoen DR, Pappot H, Csabai I, Brunak S, Mouw KW, Szallasi Z. Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2021.

Geva A, Albert BD, Hamilton S, Manning MJ, Barrett MK, Mirchandani D, Harty M, Morgan EC, Kleinman ME, Mehta NM. eSIMPLER: A Dynamic, Electronic Health Record-Integrated Checklist for Clinical Decision Support During PICU Daily Rounds. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2021.

Li J, Tiwari A, Mirzakhani H, Wang AL, Kho AT, McGeachie MJ, Litonjua AA, Weiss ST, Tantisira KG. Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification. Journal of personalized medicine 2021.

Larsen RJ, Gagoski B, Morton SU, Ou Y, Vyas R, Litt J, Grant PE, Sutton BP. Quantification of magnetic resonance spectroscopy data using a combined reference: Application in typically developing infants. NMR in biomedicine 2021.