A research assistant position is available at Dr. Kong’s group in the Computational Health Informatics Program at Boston Children’s Hospital, Boston, MA, USA. The group seeks to improve current clinical practices by providing expertise and insight from large­-scale and multi-­dimensional analysis in data­-sets from patients with neurodevelopmental conditions and other disorders.

 

The position is available for a motivated individual with expertise in data management and statistical analysis to provide insights from diverse multi­dimensional datasets in different frameworks, involving genotypes, diseases phenotypes and metabolomics.

 

PRIMARY DUTIES AND RESPONSIBILITIES:

 

  • Manage high-dimensional datasets.
  • Apply statistical methods for exploratory analysis to understand the association within and between different datasets.
  • Ensure accurate and statistically valid deliverables, including drafting statistical analysis plans and participating in writing study reports and manuscripts.
  • Work independently on multiple ongoing projects with flexibility to adjust to new priorities.
  • Manage projects for integrity of data generation and ingestion.
  • Present the work in form of scientific publications and oral communications to the scientific community.

 

The group is located at Landmark Center, belonging to Boston Children’s Hospital, a teaching hospital affiliated with Harvard University. 

Qualifications
  • Proficiency with data management and analysis in R and database is required, experience with python and shell scripting is desirable.
  • Ability to organize datasets and connect them using matching ID as well as prepare them for downstream statistical analysis.
  • Familiarity with modern data analysis paradigms is required.
  • Strong communication skills and ability to effectively translate scientific concepts to multidisciplinary personnel.
  • Highly proficient in spoken and written English and professional communication.
  • Self-motivation to learn biological knowledge, statistical methods and visualization tools based on the need of the research projects.
How to apply

Interested applicants should send a cover letter outlining research experience, skills and interests, curriculum vitae (CV), and the names and contacts of two referees to Dr. Sek Won Kong (sekwon.kong@childrens.harvard.edu).

Publications

Hopper RK, Abman SH, Elia EG, Avitabile CM, Yung D, Mullen MP, Austin ED, Bates A, Handler SS, Feinstein JA, Ivy DD, Kinsella JP, Mandl KD, Raj JU, Sleeper LA, . Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry. The Journal of pediatrics 2022.

Wang X, Zhang HG, Xiong X, Hong C, Weber GM, Brat GA, Bonzel CL, Luo Y, Duan R, Palmer NP, Hutch MR, Gutiérrez-Sacristán A, Bellazzi R, Chiovato L, Cho K, Dagliati A, Estiri H, García-Barrio N, Griffier R, Hanauer DA, Ho YL, Holmes JH, Keller MS, Klann MEng JG, L'Yi S, Lozano-Zahonero S, Maidlow SE, Makoudjou A, Malovini A, Moal B, Moore JH, Morris M, Mowery DL, Murphy SN, Neuraz A, Yuan Ngiam K, Omenn GS, Patel LP, Pedrera-Jiménez M, Prunotto A, Jebathilagam Samayamuthu M, Sanz Vidorreta FJ, Schriver ER, Schubert P, Serrano-Balazote P, South AM, Tan ALM, Tan BWL, Tibollo V, Tippmann P, Visweswaran S, Xia Z, Yuan W, Zöller D, Kohane IS, Avillach P, Guo Z, Cai T, . SurvMaximin: Robust federated approach to transporting survival risk prediction models. Journal of biomedical informatics 2022.

Torous J, Stern AD, Bourgeois FT. Regulatory considerations to keep pace with innovation in digital health products. NPJ digital medicine 2022.

Levy S, Wisk LE, Minegishi M, Ertman B, Lunstead J, Brogna M, Weitzman ER. Association of Screening and Brief Intervention With Substance Use in Massachusetts Middle and High Schools. JAMA network open 2022.

Nielsen M, Presti M, Sztupinszki Z, Jensen AWP, Draghi A, Chamberlain CA, Schina A, Yde CW, Wojcik J, Szallasi Z, Crowther MD, Svane IM, Donia M. Co-existing alterations of MHC class I antigen presentation and IFNγ signaling mediate acquired resistance of melanoma to post-PD-1 immunotherapy. Cancer immunology research 2022.