The Age of Predictive Medicine

Speaker: Ben Reis, PhD, at Boston Children's Hospital

Date: October 16, 2020 at 09:30AM - 10:30AM

Dr. Ben Reis discussed recent developments in machine learning approaches to some of the grandest challenges of human health, including pandemic prediction, suicide prevention, bioterrorism detection, and drug safety prediction. The focus was on understanding both the methodological challenges involved and the ramifications of generating actionable predictions in these critical areas. The talk concluded by formulating a set of central challenges and opportunities facing the field of Predictive Medicine.

Dr. Ben Reis is the Director of the Predictive Medicine Group at the Computational Health Informatics Program at Boston Children's Hospital and Harvard Medical School. His research focuses on understanding the fundamental patterns of human disease and on developing novel approaches for predicting disease. He has created systems that allow doctors to predict dangerous clinical conditions years in advance, including suicide and domestic abuse, as well as predictive pharmacology systems that allow drug safety professionals to identify life-threatening adverse drug effects years in advance. Dr. Reis has advised the US government on establishing national biodefense systems in the wake of the 9/11 attacks, the Hong Kong government on building health infrastructure in response to the SARS pandemic, the Greek government on establishing biodefense systems for the Athens Summer Olympics, and the Chinese Government in advance of the Beijing Summer Olympics. He has been honored at the White House for his work on harnessing social networks to promote health, and was named one of the top health innovators in the world by the US State Department and NASA.


Publications

Chen KY, Borglund EM, Postema EC, Dunn AG, Bourgeois FT. Reporting of clinical trial safety results in ClinicalTrials.gov for FDA-approved drugs: A cross-sectional analysis. Clinical trials (London, England) 2022.

Le Naour J, Sztupinszki Z, Carbonnier V, Casiraghi O, Marty V, Galluzzi L, Szallasi Z, Kroemer G, Vacchelli E. A loss-of-function polymorphism in compromises therapeutic outcome in head and neck carcinoma patients. Oncoimmunology 2022.

Klann JG, Strasser ZH, Hutch MR, Kennedy CJ, Marwaha JS, Morris M, Samayamuthu MJ, Pfaff AC, Estiri H, South AM, Weber GM, Yuan W, Avillach P, Wagholikar KB, Luo Y, Omenn GS, Visweswaran S, Holmes JH, Xia Z, Brat GA, Murphy SN. Distinguishing Admissions Specifically for COVID-19 from Incidental SARS-CoV-2 Admissions: A National Retrospective EHR Study. Journal of medical Internet research 2022.