The Age of Predictive Medicine

Speaker: Ben Reis, PhD, at Boston Children's Hospital

Date: October 16, 2020 at 09:30AM - 10:30AM

Dr. Ben Reis discussed recent developments in machine learning approaches to some of the grandest challenges of human health, including pandemic prediction, suicide prevention, bioterrorism detection, and drug safety prediction. The focus was on understanding both the methodological challenges involved and the ramifications of generating actionable predictions in these critical areas. The talk concluded by formulating a set of central challenges and opportunities facing the field of Predictive Medicine.

Dr. Ben Reis is the Director of the Predictive Medicine Group at the Computational Health Informatics Program at Boston Children's Hospital and Harvard Medical School. His research focuses on understanding the fundamental patterns of human disease and on developing novel approaches for predicting disease. He has created systems that allow doctors to predict dangerous clinical conditions years in advance, including suicide and domestic abuse, as well as predictive pharmacology systems that allow drug safety professionals to identify life-threatening adverse drug effects years in advance. Dr. Reis has advised the US government on establishing national biodefense systems in the wake of the 9/11 attacks, the Hong Kong government on building health infrastructure in response to the SARS pandemic, the Greek government on establishing biodefense systems for the Athens Summer Olympics, and the Chinese Government in advance of the Beijing Summer Olympics. He has been honored at the White House for his work on harnessing social networks to promote health, and was named one of the top health innovators in the world by the US State Department and NASA.


Publications

Levy S, Wisk LE, Chadi N, Lunstead J, Shrier LA, Weitzman ER. Validation of a single question for the assessment of past three-month alcohol consumption among adolescents. Drug and alcohol dependence 2021.

Wu F, Xiao A, Zhang J, Moniz K, Endo N, Armas F, Bonneau R, Brown MA, Bushman M, Chai PR, Duvallet C, Erickson TB, Foppe K, Ghaeli N, Gu X, Hanage WP, Huang KH, Lee WL, Matus M, McElroy KA, Nagler J, Rhode SF, Santillana M, Tucker JA, Wuertz S, Zhao S, Thompson J, Alm EJ. SARS-CoV-2 RNA concentrations in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases. The Science of the total environment 2021.

Weber GM, Zhang HG, L'Yi S, Bonzel CL, Hong C, Avillach P, Gutiérrez-Sacristán A, Palmer NP, Tan AL, Wang X, Yuan W, Gehlenborg N, Alloni A, Amendola DF, Bellasi A, Bellazzi R, Beraghi M, Bucalo M, Chiovato L, Cho K, Dagliati A, Estiri H, Follett RW, García-Barrio N, Hanauer DA, Henderson DW, Ho YL, Holmes JH, Hutch MR, Kavuluru R, Kirchoff K, Klann JG, Krishnamurthy AK, Le TT, Liu M, Loh NHW, Lozano-Zahonero S, Luo Y, Maidlow S, Makoudjou A, Malovini A, Moal B, Morris M, Mowery DL, Murphy SN, Neuraz A, Ngiam KY, Okoshi MP, Omenn GS, Patel LP, Pedrera-Jiménez M, Prudente RA, Samayamuthu MJ, Sanz J, Schriver ER, Schubert P, Serrano-Balazote P, Tan BW, Tanni SE, Tibollo V, Visweswaran S, Wagholikar KB, Xia Z, Zöller D, Kohane IS, Cai T, South AM, Brat GA. International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: a 4CE Consortium Study. Journal of medical Internet research 2021.

Mandl KD, Perakslis ED. HIPAA and the Leak of "Deidentified" EHR Data. Reply. The New England journal of medicine 2021.

Rees CA, Monuteaux MC, Herdell V, Fleegler EW, Bourgeois FT. Correlation Between National Institutes of Health Funding for Pediatric Research and Pediatric Disease Burden in the US. JAMA pediatrics 2021.