John Brownstein, PhD

Assistant Professor of Pediatrics
Harvard Medical School
Director, Computational Epidemiology Group

affiliation	Children's Hospital Boston Harvard-MIT Division of Health Sciences and Technology Harvard Medical School
research	spatial temporal models of infectious diseases; outbreak detection; application of real-time surveillance systems for disease control strategies; www.healthmap.org; post-marketing drug safety;
address	1 Autumn St Room 541 Boston, MA 02215
email	john_brownstein@harvard.edu
homepage	http://www.chip.org/research/people/john_brownstein.htm
phone	617-355-6998
fax	617-730-0267
publication	Brownstein JS, Freifeld CC. Madoff L. 2009. Influenza A (H1N1) virus, 2009—online monitoring. New England Journal of Medicine. May 21;360(21):2156 Brownstein JS, Freifeld CC. Madoff L. 2009. Digital Disease Detection: Harnessing the Web for Public Health Surveillance. New England Journal of Medicine. May 21;360(21):2153-5, 2157 Wilson K, Brownstein JS. 2009. Early detection of disease outbreaks using the Internet. Canadian Medical Association Journal. Apr 14;180(8):829-31 Keller M, Blench M, Tolentino H, Freifeld CC, Mandl KD, Mawedeku A, Eysenbach, G, Brownstein JS. 2009. Early Experiences in Real-time Automated Global Infectious Disease Surveillance, Using Unstructured Event-based Reports. Emerging Infectious Diseases. May;15(5):689-95 Charland KML, Buckeridge DL, Sturtevant JL, Melton F, Reis BY, Mandl KD, Brownstein JS. 2008. Effect of environmental factors on the spatio-temporal patterns of influenza spread in the United States. Epidemiology and Infection. Mar 19:1-11. Brei B, Brownstein JS, George JE, Pound M, Miller A, Daniels TJ, Falco RC, Stafford KC, Schulze TL, Mather TN, Carroll JF, Fish D. Evaluation of the USDA Northeast Area-wide Tick Control Project by Meta-analysis. Vector Borne Zoonotic Diseases. 2009 Aug;9(4):423-30. Butler SG, Budman SH, Licari A, Cassidy TA, Lioy K, Dickinson J, Brownstein JS, Bennyan JC, Greent TC, Katz N. 2008. National addictions vigilance intervention and prevention program (NAVIPPRO): a real-time, product-specific, public health surveillance system for monitoring prescription drug abuse. Pharmacoepidemiol Drug Saf. Dec;17(12):1142-54. Brownstein J.S., Mandl, K.D. 2008 Pediatric population size is associated with geographic patterns of acute respiratory infections among adults. Ann Emerg Med. Jul;52(1):63-8. Epub 2008 Mar 28. Bourgeois F.T., Simons W.W., Olson K., Brownstein J.S., Mandl K.D. 2008. Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial. J Med Internet Res. Mar 14;10(1):e5. Brownstein J.S., Freifeld C.C., Reis B.Y., Mandl K.D. 2008. Surveillance Sans Frontiere: Internet-Based Emerging Infectious Disease Intelligence and the HealthMap Project. PLoS Medicine. 5(7): E151. Sebastian R, Skowronski DM, Chong M, Dhaliwal J, Brownstein JS. Age-related trends in the timeliness and prediction of medical visits, hospitalizations and deaths due to pneumonia and influenza, British Columbia, Canada, 1998-2004. Vaccine. 2008 Mar 4;26(10):1397-403. Epub 2007 Dec 26. Anema A, Mills E, Montaner J, Brownstein JS, Cooper C. Efficacy of influenza vaccination in HIV-positive patients: a systematic review and meta-analysis. HIV Med. 2008 Jan;9(1):57-61. Brownstein CA, Brownstein JS. Estimating excess mortality in post-invasion Iraq. N Engl J Med. 2008 Jan 31;358(5):445-7. Epub 2008 Jan 9. Freifeld CC, Mandl KD, Reis BY, Brownstein JS. HealthMap: Global infectious disease monitoring through automated classification and visualization of Internet media reports. J Am Med Inform Assoc. 2007 Dec 20 Brownstein JS, Freifeld CC. HealthMap: the development of automated real-time internet surveillance for epidemic intelligence. Euro Surveill. 2007 Nov 29;12(11):E071129.5. Brownstein JS, Sordo M, Kohane IS, Mandl KD. The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction. PLoS ONE. 2007 Sep 5;2(9):e840. Wieland SC, Brownstein JS, Berger B, Mandl KD. Automated real time constant-specificity surveillance for disease outbreaks. BMC Med Inform Decis Mak. 2007 Jun 13;7:15. Wieland SC, Brownstein JS, Berger B, Mandl KD. Density-equalizing Euclidean minimum spanning trees for the detection of all disease cluster shapes. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9404-9. Epub 2007 May 22. Brownstein JS, Cassa CA, Mandl KD. 2006. No place to hide: Re-identifying patients from published maps. New England Journal of Medicine. 355(16):1741-2. Brownstein JS, Cassa CA, Kohane, IS, Mandl KD. 2006. An unsupervised classification method for inferring original case locations form low-resolution maps. International Journal of Health Geographics. Dec 8:5:56. Brownstein JS, Wolfe CJ, Mandl KD. 2006. Empirical Evidence for the effect of airline travel on inter-regional influenza spread in the United States. PLoS Medicine. Sept.3(10): e401. Kimia A, Brownstein JS, Olson KL, Zak V, Bourgeois FT, Mandl KD. Lumbar puncture ordering and results in the pediatric population: a promising data source for surveillance systems. Acad Emerg Med.[In Press] Diuk-Wasser, M.A, Gatewood, A.G., Cortinas, M.R., Yaremych-Hamer, S.; Tsao, J., Kitron, U., Hickling, G.; Brownstein, J.S.; Walker, E., Piesman, J., Fish D. 2006. Spatiotemporal Patterns of Host-Seeking Ixodes scapularis Nymphs (Acari: Ixodidae) in the United States. Journal of Medical Entomology. 42(2): 166-176. Bourgeois, F.T., Olson, K.L., Brownstein, J. S., McAdam. A.J., Mandl, K.D. 2006. Validation of syndromic surveillance for respiratory infections. Annals of Emergency Medicine. 47:3:265 e1. Brownstein, JS, Kleinman, K.P, Mandl, KD. 2005. Identifying pediatric age groups for influenza vaccination using a real-time regional surveillance system. American Journal of Epidemiology. Oct 1;162(7):686-93. Brownstein, J.S., Skelly, D. K., Holford, T.R., Fish, D. 2005. Forest fragmentation predicts local scale heterogeneity of Lyme disease risk. Oecologia. Sep 27:1-7. Brownstein, JS, Olson, KL, Kleinman, K.P, Mandl, KD. 2006. Timeliness of health care encounter data for syndromic surveillance. MMWR. 2005; (Supplement: Syndromic Surveillance: Reports from a National Conference, 2004). Reis, B.Y., Brownstein J.S., Mandl K.D. 2005. Running the Baseline: Impact of the 2005 Major League Baseball postseason on emergency department us. Annals of Emergency Medicine. 46(4):386-7. Brownstein, JS, Holford, TR, Fish, D. 2004. Forecasting the impact of climate change on future Lyme disease risk in North America. Ecohealth; 2(1):38-46. Derdakova, M., Dudioak, V., Brei, B, Brownstein, J.S., Schwartz, I.., Fish, D., 2004. Transmission and interaction of two Borrelia burgdorferi sensu strico strains in a tick-rodent maintenance system. Applied and Environmental Microbiology:70(11):6783-8. Brownstein, J.S., Holford, T.R., Fish, D., 2004 Enhancing West Nile Virus surveillance, United States. Emerging Infectious Diseases: 10(6). 1129-1133. Madhav, N. K., Brownstein, J. S., Tsao, J. I., Fish, D. 2003. A dispersal model for the range expansion of the blacklegged tick, Ixodes scapularis (Acari: Ixodidae). Journal of Medical Entomology:41(5). 842-852. Brownstein, J.S., Holford, T.R., Fish, D., 2003. A climate-based model predicts the spatial distribution of the Lyme disease vector Ixodes scapularis in the United States. Environmental Health Perspectives: 111(9). 1152-1157. Brownstein, J.S., Hett, E., O'Neill, S.L. 2003. Virulent Wolbachia as a tool to modify insect vector competence for dengue transmission. Journal of Invertebrate Pathology: 84(1). 24-29. Brownstein, J.S., Rosen, H., Purdy, D., Miller, J., Merlino, M., Mostashari, F., Fish, D., 2002. Spatial analysis of West Nile Virus: Rapid risk assessment of an introduced vector-borne zoonosis. Vector Borne and Zoonotic Diseases. 2(3): 157-164. Schoen, D.J., Brownstein, J.S., White, P.A., 2002. Mutation load in natural populations of the sensitive fern Onoclea sensibilis exposed to soil mutagens. Ecological Applications 12, 124-137.