Intelligent Health Lab

Instructor, Harvard Medical School

Faculty, Children's Hospital Informatics Program at the

Harvard-MIT Division of  Health Sciences and Technology

Affiliated Faculty, Harvard-MIT Division of Health, Sciences & Technology

Faculty, Division of Emergency Medicine, Children's Hospital Boston

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Email: john_brownstein@harvard.edu

Phone: 617-355-6998

EDUCATION

Public Health Surveillance

Novel statistical modeling approaches for public health surveillance

Developing algorithms for detection of emerging infections, epidemics, outbreaks, attacks

Post-marketing surveillance of adverse drug events and prescripion opioid abuse

Global web-based surveillance: the Healthmap project (www.healthmap.org)

Epidemiology of Infectious Diseases

Modeling patterns in infectious disease surveillance data to improve public health control strategies.

Recent research projects have focused on spatiotemporal trends in influenza epidemics and pandemics to inform control strategies such as vaccination and quarantine

Spatial and Landscape Epidemiology

Understanding environmental factors that influence zoonotic disease risk

Developing risk maps through the application of geographic information systems, remote sensing and geostatistics.

Infectious Disease Epidemiology and Surveillance
Brownstein JS, Cassa CA, Mandl KD. 2006. No place to hide: Re-identifying patients from published maps. New England Journal of Medicine. 355(16):1741-2.

Brownstein JS, Cassa CA, Kohane, IS, Mandl KD. 2006. An unsupervised classification method for inferring original case locations form low-resolution maps. International Journal of Health Geographics. Dec 8:5:56.

Brownstein JS, Wolfe CJ, Mandl KD. 2006. Empirical Evidence for the effect of airline travel on inter-regional influenza spread in the United States. PLoS Medicine. Sept.3(10): e401.

Kimia A, Brownstein JS, Olson KL, Zak V, Bourgeois FT, Mandl KD. 2006. Lumbar puncture ordering and results in the pediatric population: a promising data source for surveillance systems. Acad Emerg Med. Jul;13(7):767-73

Bourgeois, F.T., Olson, K.L., Brownstein, J. S., McAdam. A.J., Mandl, K.D. 2006. Validation of syndromic surveillance for respiratory infections. Annals of Emergency Medicine. 47:3:265 e1.

Bourgeois, F.T., Olson, K.L., Brownstein, J. S., McAdam. A.J., Mandl, K.D. 2006. Validation of syndromic surveillance for respiratory infections. Annals of Emergency Medicine. 47:3:265 e1.

Brownstein, JS, Kleinman, K.P, Mandl, KD. 2005. Identifying pediatric age groups for influenza vaccination using a real-time regional surveillance system. American Journal of Epidemiology. Oct 1;162(7):686-93.

Brownstein, JS, Olson, KL, Kleinman, K.P, Mandl, KD. 2006. Timeliness of health care encounter data for syndromic surveillance. MMWR. 2005; (Supplement: Syndromic Surveillance: Reports from a National Conference, 2004).

Reis, B.Y., Brownstein J.S., Mandl K.D. 2005. Running the Baseline: Impact of the 2005 Major League Baseball postseason on emergency department us. Annals of Emergency Medicine. 46(4):386-7.

Brownstein, J.S., Holford, T.R., Fish, D., 2004 Enhancing West Nile Virus surveillance, United States. Emerging Infectious Diseases: 10(6). 1129-1133.

Spatial/Landscape Epidemiology
Diuk-Wasser, M.A, Gatewood, A.G., Cortinas, M.R., Yaremych-Hamer, S.; Tsao, J., Kitron, U., Hickling, G.; Brownstein, J.S.; Walker, E., Piesman, J., Fish D. 2006. Spatiotemporal Patterns of Host-Seeking Ixodes scapularis Nymphs (Acari: Ixodidae) in the United States. Journal of Medical Entomology. 42(2): 166-176.

Brownstein, J.S., Skelly, D. K., Holford, T.R., Fish, D. 2005. Forest fragmentation predicts local scale heterogeneity of Lyme disease risk. Oecologia. Sep 27:1-7.

Brownstein, JS, Holford, TR, Fish, D. 2004. Forecasting the impact of climate change on future Lyme disease risk in North America. Ecohealth; 2(1):38-46.

Madhav, N. K., Brownstein, J. S., Tsao, J. I., Fish, D. 2003. A dispersal model for the range expansion of the blacklegged tick, Ixodes scapularis (Acari: Ixodidae). Journal of Medical Entomology:41(5). 842-852.

Brownstein, J.S., Holford, T.R., Fish, D., 2003. A climate-based model predicts the spatial distribution of the Lyme disease vector Ixodes scapularis in the United States. Environmental Health Perspectives: 111(9). 1152-1157.

Brownstein, J.S., Rosen, H., Purdy, D., Miller, J., Merlino, M., Mostashari, F., Fish, D., 2002. Spatial analysis of West Nile Virus: Rapid risk assessment of an introduced vector-borne zoonosis. Vector Borne and Zoonotic Diseases. 2(3): 157-164.

Population Genetics

Derdakova, M., Dudioak, V., Brei, B, Brownstein, J.S., Schwartz, I.., Fish, D., 2004. Transmission and interaction of two Borrelia burgdorferi sensu strico strains in a tick-rodent maintenance system. Applied and Environmental Microbiology:70(11):6783-8.

Brownstein, J.S., Hett, E., O'Neill, S.L. 2003. Virulent Wolbachia as a tool to modify insect vector competence for dengue transmission. Journal of Invertebrate Pathology: 84(1). 24-29.

Schoen, D.J., Brownstein, J.S., White, P.A., 2002. Mutation load in natural populations of the sensitive fern Onoclea sensibilis exposed to soil mutagens. Ecological Applications 12, 124-137.

NPR. Shots for Kids May Be Best Flu Defense. October 5, 2005.

USA Today. Flu Season Begins With Preschoolers, Study Confirms. October 4, 2005.

MSNBC. Vaccinating Kids May Prevent Spread of Flu. October 3, 2005.

Harvard Gazette. ER Takes Backseat to Ballgames. Sept 29, 2004.

New York Times. Patterns: Red Sox Fever and the Lonely Emergency Room. September 27, 2005.

Scientific American. Watching World Series Causes Drop in Hospital Visits. September 26, 2005.