Levy S, Wisk LE, Chadi N, Lunstead J, Shrier LA, Weitzman ER. Validation of a single question for the assessment of past three-month alcohol consumption among adolescents. Drug and alcohol dependence 2021.

Wu F, Xiao A, Zhang J, Moniz K, Endo N, Armas F, Bonneau R, Brown MA, Bushman M, Chai PR, Duvallet C, Erickson TB, Foppe K, Ghaeli N, Gu X, Hanage WP, Huang KH, Lee WL, Matus M, McElroy KA, Nagler J, Rhode SF, Santillana M, Tucker JA, Wuertz S, Zhao S, Thompson J, Alm EJ. SARS-CoV-2 RNA concentrations in wastewater foreshadow dynamics and clinical presentation of new COVID-19 cases. The Science of the total environment 2021.

Weber GM, Zhang HG, L'Yi S, Bonzel CL, Hong C, Avillach P, Gutiérrez-Sacristán A, Palmer NP, Tan AL, Wang X, Yuan W, Gehlenborg N, Alloni A, Amendola DF, Bellasi A, Bellazzi R, Beraghi M, Bucalo M, Chiovato L, Cho K, Dagliati A, Estiri H, Follett RW, García-Barrio N, Hanauer DA, Henderson DW, Ho YL, Holmes JH, Hutch MR, Kavuluru R, Kirchoff K, Klann JG, Krishnamurthy AK, Le TT, Liu M, Loh NHW, Lozano-Zahonero S, Luo Y, Maidlow S, Makoudjou A, Malovini A, Moal B, Morris M, Mowery DL, Murphy SN, Neuraz A, Ngiam KY, Okoshi MP, Omenn GS, Patel LP, Pedrera-Jiménez M, Prudente RA, Samayamuthu MJ, Sanz J, Schriver ER, Schubert P, Serrano-Balazote P, Tan BW, Tanni SE, Tibollo V, Visweswaran S, Wagholikar KB, Xia Z, Zöller D, Kohane IS, Cai T, South AM, Brat GA. International Changes in COVID-19 Clinical Trajectories Across 315 Hospitals and 6 Countries: a 4CE Consortium Study. Journal of medical Internet research 2021.

Mandl KD, Perakslis ED. HIPAA and the Leak of "Deidentified" EHR Data. Reply. The New England journal of medicine 2021.

Rees CA, Monuteaux MC, Herdell V, Fleegler EW, Bourgeois FT. Correlation Between National Institutes of Health Funding for Pediatric Research and Pediatric Disease Burden in the US. JAMA pediatrics 2021.

Wang F, Yang S, Palmer N, Fox K, Kohane IS, Liao KP, Yu KH, Kou SC. Real-world data analyses unveiled the immune-related adverse effects of immune checkpoint inhibitors across cancer types. NPJ precision oncology 2021.

El Halabi J, Palmer N, Fox K, Kohane I, Farhat MR. Fecal microbiota transplantation and Clostridioides difficile infection among privately insured patients in the United States. Journal of gastroenterology 2021.

Dagan N, Barda N, Biron-Shental T, Makov-Assif M, Key C, Kohane IS, Hernán MA, Lipsitch M, Hernandez-Diaz S, Reis BY, Balicer RD. Effectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy. Nature medicine 2021.

Sadilek A, Liu L, Nguyen D, Kamruzzaman M, Serghiou S, Rader B, Ingerman A, Mellem S, Kairouz P, Nsoesie EO, MacFarlane J, Vullikanti A, Marathe M, Eastham P, Brownstein JS, Arcas BAY, Howell MD, Hernandez J. Privacy-first health research with federated learning. NPJ digital medicine 2021.

Geva A, Patel MM, Newhams MM, Young CC, Son MBF, Kong M, Maddux AB, Hall MW, Riggs BJ, Singh AR, Giuliano JS, Hobbs CV, Loftis LL, McLaughlin GE, Schwartz SP, Schuster JE, Babbitt CJ, Halasa NB, Gertz SJ, Doymaz S, Hume JR, Bradford TT, Irby K, Carroll CL, McGuire JK, Tarquinio KM, Rowan CM, Mack EH, Cvijanovich NZ, Fitzgerald JC, Spinella PC, Staat MA, Clouser KN, Soma VL, Dapul H, Maamari M, Bowens C, Havlin KM, Mourani PM, Heidemann SM, Horwitz SM, Feldstein LR, Tenforde MW, Newburger JW, Mandl KD, Randolph AG, . Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine 2021.

Feldman TC, Dienstag JL, Mandl KD, Tseng YJ. Machine-learning-based predictions of direct-acting antiviral therapy duration for patients with hepatitis C. International journal of medical informatics 2021.

Laparra E, Mascio A, Velupillai S, Miller T. A Review of Recent Work in Transfer Learning and Domain Adaptation for Natural Language Processing of Electronic Health Records. Yearbook of medical informatics 2021.

Abramoff MD, Cunningham B, Patel B, Eydelman MB, Leng T, Sakamoto T, Blodi B, Grenon SM, Wolf RM, Manrai AK, Ko JM, Chiang MF, Char D, . Foundational Considerations for Artificial Intelligence Utilizing Ophthalmic Images. Ophthalmology 2021.

Santoro JD, Kerr LM, Codden R, Casper TC, Greenberg BM, Waubant E, Kong SW, Mandl KD, Gorman MP. Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome. Neurology(R) neuroimmunology & neuroinflammation 2021.

Wang X, Cai T, Tian L, Bourgeois F, Parast L. Quantifying the feasibility of shortening clinical trial duration using surrogate markers. Statistics in medicine 2021.

Shapiro DJ, Palmer NP, Bourgeois FT. Factors Associated With Corticosteroid Treatment for Pediatric Acute Respiratory Tract Infections. Journal of the Pediatric Infectious Diseases Society 2021.

He S, Ellen Grant P, Ou Y. Global-Local Transformer for Brain Age Estimation. IEEE transactions on medical imaging 2021.

Levy S, Evins AE, Schuster RM, Green L, Lunstead J, Fuller A, Needles EW, Weitzman ER. Virtual Group Therapy Programs-The Wave of the Future. The Journal of adolescent health : official publication of the Society for Adolescent Medicine 2021.

Kreps SE, Goldfarb JL, Brownstein JS, Kriner DL. The Relationship between US Adults' Misconceptions about COVID-19 Vaccines and Vaccination Preferences. Vaccines 2021.

Barda N, Dagan N, Ben-Shlomo Y, Kepten E, Waxman J, Ohana R, Hernán MA, Lipsitch M, Kohane I, Netzer D, Reis BY, Balicer RD. Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting. The New England journal of medicine 2021.

Gutiérrez-Sacristán A, Sáez C, De Niz C, Jalali N, DeSain TN, Kumar R, Zachariasse JM, Fox KP, Palmer N, Kohane I, Avillach P. Multi-PheWAS intersection approach to identify sex differences across comorbidities in 59 140 pediatric patients with autism spectrum disorder. Journal of the American Medical Informatics Association : JAMIA 2021.

Obstfeld AE, Patel K, , Boyd JC, Drees J, Holmes DT, Ioannidis JPA, Manrai AK. Data Mining Approaches to Reference Interval Studies. Clinical chemistry 2021.

Sztupinszki Z, Diossy M, Börcsök J, Prosz A, Cornelius N, Kjeldsen MK, Mirza MR, Szallasi Z. Comparative Assessment of Diagnostic Homologous Recombination Deficiency associated mutational signatures in ovarian cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2021.

Perlis RH, Ognyanova K, Quintana A, Green J, Santillana M, Lin J, Druckman J, Lazer D, Simonson MD, Baum MA, Chwe H. Gender-specificity of resilience in major depressive disorder. Depression and anxiety 2021.

Thorpe Huerta D, Hawkins JB, Brownstein JS, Hswen Y. Exploring discussions of health and risk and public sentiment in Massachusetts during COVID-19 pandemic mandate implementation: A Twitter analysis. SSM - population health 2021.

Yu X, Ferradal SL, Sliva DD, Dunstan J, Carruthers C, Sanfilippo J, Zuk J, Zöllei L, Boyd E, Gagoski B, Ou Y, Grant PE, Gaab N. Functional Connectivity in Infancy and Toddlerhood Predicts Long-Term Language and Preliteracy Outcomes. Cerebral cortex (New York, N.Y. : 1991) 2021.

Weitzman ER, Sherman AC, Levy O. SARS-CoV-2 mRNA Vaccine Attitudes as Expressed in U.S. FDA Public Commentary: Need for a Public-Private Partnership in a Learning Immunization System. Frontiers in public health 2021.

Diao JA, Powe NR, Manrai AK. Race-Free Equations for eGFR: Comparing Effects on CKD Classification. Journal of the American Society of Nephrology : JASN 2021.

Plana D, Tian E, Cramer AK, Yang H, Carmack MM, Sinha MS, Bourgeois FT, Yu SH, Masse P, Boyer J, Kim M, Mo J, LeBoeuf NR, Li J, Sorger PK. Assessing the filtration efficiency and regulatory status of N95s and nontraditional filtering face-piece respirators available during the COVID-19 pandemic. BMC infectious diseases 2021.

Cromwell EA, Osborne JCP, Unnasch TR, Basáñez MG, Gass KM, Barbre KA, Hill E, Johnson KB, Donkers KM, Shirude S, Schmidt CA, Adekanmbi V, Adetokunboh OO, Afarideh M, Ahmadpour E, Ahmed MB, Akalu TY, Al-Aly Z, Alanezi FM, Alanzi TM, Alipour V, Andrei CL, Ansari F, Ansha MG, Anvari D, Appiah SCY, Arabloo J, Arnold BF, Ausloos M, Ayanore MA, Baig AA, Banach M, Barac A, Bärnighausen TW, Bayati M, Bhattacharyya K, Bhutta ZA, Bibi S, Bijani A, Bohlouli S, Bohluli M, Brady OJ, Bragazzi NL, Butt ZA, Carvalho F, Chatterjee S, Chattu VK, Chattu SK, Cormier NM, Dahlawi SMA, Damiani G, Daoud F, Darwesh AM, Daryani A, Deribe K, Dharmaratne SD, Diaz D, Do HT, El Sayed Zaki M, El Tantawi M, Elemineh DA, Faraj A, Fasihi Harandi M, Fatahi Y, Feigin VL, Fernandes E, Foigt NA, Foroutan M, Franklin RC, Gubari MIM, Guido D, Guo Y, Haj-Mirzaian A, Hamagharib Abdullah K, Hamidi S, Herteliu C, Hidru HD, Higazi TB, Hossain N, Hosseinzadeh M, Househ M, Ilesanmi OS, Ilic MD, Ilic IM, Iqbal U, Irvani SSN, Jha RP, Joukar F, Jozwiak JJ, Kabir Z, Kalankesh LR, Kalhor R, Karami Matin B, Karimi SE, Kasaeian A, Kavetskyy T, Kayode GA, Kazemi Karyani A, Kelbore AG, Keramati M, Khalilov R, Khan EA, Khan MNN, Khatab K, Khater MM, Kianipour N, Kibret KT, Kim YJ, Kosen S, Krohn KJ, Kusuma D, La Vecchia C, Lansingh VC, Lee PH, LeGrand KE, Li S, Longbottom J, Magdy Abd El Razek H, Magdy Abd El Razek M, Maleki A, Mamun AA, Manafi A, Manafi N, Mansournia MA, Martins-Melo FR, Mazidi M, McAlinden C, Meharie BG, Mendoza W, Mengesha EW, Mengistu DT, Mereta ST, Mestrovic T, Miller TR, Miri M, Moghadaszadeh M, Mohammadian-Hafshejani A, Mohammadpourhodki R, Mohammed S, Mohammed S, Moradi M, Moradzadeh R, Moraga P, Mosser JF, Naderi M, Nagarajan AJ, Naik G, Negoi I, Nguyen CT, Nguyen HLT, Nguyen TH, Nikbakhsh R, Oancea B, Olagunju TO, Olagunju AT, Omar Bali A, Onwujekwe OE, Pana A, Pourjafar H, Rahim F, Rahman MHU, Rathi P, Rawaf S, Rawaf DL, Rawassizadeh R, Resnikoff S, Reta MA, Rezapour A, Rubagotti E, Rubino S, Sadeghi E, Saghafipour A, Sajadi SM, Samy AM, Sarmiento-Suárez R, Sawhney M, Schipp MF, Shaheen AA, Shaikh MA, Shamsizadeh M, Sharafi K, Sheikh A, Shetty BSK, Shin JI, Shivakumar KM, Simonetti B, Singh JA, Skiadaresi E, Soheili A, Soltani S, Spurlock EE, Sufiyan MB, Tabuchi T, Tapak L, Thompson RL, Thomson AJ, Traini E, Tran BX, Ullah I, Ullah S, Uneke CJ, Unnikrishnan B, Uthman OA, Vinkeles Melchers NVS, Violante FS, Wolde HF, Wonde TE, Yamada T, Yaya S, Yazdi-Feyzabadi V, Yip P, Yonemoto N, Yousof HSA, Yu C, Yu Y, Yusefzadeh H, Zaki L, Zaman SB, Zamanian M, Zhang ZJ, Zhang Y, Ziapour A, Hay SI, Pigott DM. Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning. PLoS neglected tropical diseases 2021.

Hutch MR, Liu M, Avillach P, , Luo Y, Bourgeois FT. National Trends in Disease Activity for COVID-19 Among Children in the US. Frontiers in pediatrics 2021.

Sudre CH, Keshet A, Graham MS, Joshi AD, Shilo S, Rossman H, Murray B, Molten E, Klaser K, Canas LD, Antonelli M, Nguyen LH, Drew DA, Modat M, Pujol JC, Ganesh S, Wolf J, Meir T, Chan AT, Steves CJ, Spector TD, Brownstein JS, Segal E, Ourselin S, Astley CM. Anosmia, ageusia, and other COVID-19-like symptoms in association with a positive SARS-CoV-2 test, across six national digital surveillance platforms: an observational study. The Lancet. Digital health 2021.

Kohane IS. Finding a new balance between a genetics-first or phenotype-first approach to the study of disease. Neuron 2021.

Hennessy EA, Acabchuk RL, Arnold PA, Dunn AG, Foo YZ, Johnson BT, Geange SR, Haddaway NR, Nakagawa S, Mapanga W, Mengersen K, Page MJ, Sánchez-Tójar A, Welch V, McGuinness LA. Ensuring Prevention Science Research is Synthesis-Ready for Immediate and Lasting Scientific Impact. Prevention science : the official journal of the Society for Prevention Research 2021.

Sathyanarayana A, El Atrache R, Jackson M, Alter AS, Mandl KD, Loddenkemper T, Bosl WJ. Measuring the effects of sleep on epileptogenicity with multifrequency entropy. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2021.

Gordon WJ, Gottlieb D, Kreda D, Mandel JC, Mandl KD, Kohane IS. Patient-led data sharing for clinical bioinformatics research: USCDI and beyond. Journal of the American Medical Informatics Association : JAMIA 2021.

Gokuldass A, Schina A, Lauss M, Harbst K, Chamberlain CA, Draghi A, Westergaard MCW, Nielsen M, Papp K, Sztupinszki Z, Csabai I, Svane IM, Szallasi Z, Jönsson G, Donia M. Transcriptomic signatures of tumors undergoing T cell attack. Cancer immunology, immunotherapy : CII 2021.

Finlayson SG, Subbaswamy A, Singh K, Bowers J, Kupke A, Zittrain J, Kohane IS, Saria S. The Clinician and Dataset Shift in Artificial Intelligence. The New England journal of medicine 2021.

Donado C, Nedeljkovic K, Wangnamthip S, Solodiuk JC, Bourgeois FT, Berde CB. Trends in Gabapentin and Pregabalin Prescribing in a Tertiary Pediatric Medical Center. Hospital pediatrics 2021.

Guo J, Zhou Y, Xu C, Chen Q, Sztupinszki Z, Börcsök J, Xu C, Ye F, Tang W, Kang J, Yang L, Zhong J, Zhong T, Hu T, Yu R, Szallasi Z, Deng X, Li Q. Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers. Cancer research 2021.

Tiwari A, Wang AL, Li J, Lutz SM, Kho AT, Weiss ST, Tantisira KG, McGeachie MJ. Seasonal Variation in miR-328-3p and let-7d-3p Are Associated With Seasonal Allergies and Asthma Symptoms in Children. Allergy, asthma & immunology research 2021.

De Brouwer W, Patel CJ, Manrai AK, Rodriguez-Chavez IR, Shah NR. Empowering clinical research in a decentralized world. NPJ digital medicine 2021.

Wu AC, Graif C, Mitchell SG, Meurer J, Mandl KD. Creative Approaches for Assessing Long-term Outcomes in Children. Pediatrics 2021.

Hswen Y, Zhang A, Brownstein JS. Estimating the incidence of cocaine use and mortality with music lyrics about cocaine. NPJ digital medicine 2021.

Zigman Suchsland ML, Rahmatullah I, Lutz B, Lyon V, Huang S, Kline E, Graham C, Cooper S, Su P, Smedinghoff S, Chu HY, Sewalk K, Brownstein JS, Thompson MJ, . Evaluating an app-guided self-test for influenza: lessons learned for improving the feasibility of study designs to evaluate self-tests for respiratory viruses. BMC infectious diseases 2021.

Diossy M, Sztupinszki Z, Borcsok J, Krzystanek M, Tisza V, Spisak S, Rusz O, Timar J, Csabai I, Fillinger J, Moldvay J, Pedersen AG, Szuts D, Szallasi Z. A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures. NPJ precision oncology 2021.

Huang Y, Yuan W, Kohane IS, Beaulieu-Jones BK. Illustrating potential effects of alternate control populations on real-world evidence-based statistical analyses. JAMIA open 2021.

Abman SH, Mullen MP, Sleeper LA, Austin ED, Rosenzweig EB, Kinsella JP, Ivy D, Hopper RK, Usha Raj J, Fineman J, Keller RL, Bates A, Krishnan US, Avitabile CM, Davidson A, Natter MD, Mandl KD, . Characterisation of Pediatric Pulmonary Hypertensive Vascular Disease from the PPHNet Registry. The European respiratory journal 2021.

Lu FS, Nguyen AT, Link NB, Molina M, Davis JT, Chinazzi M, Xiong X, Vespignani A, Lipsitch M, Santillana M. Estimating the cumulative incidence of COVID-19 in the United States using influenza surveillance, virologic testing, and mortality data: Four complementary approaches. PLoS computational biology 2021.

Aiken EL, Nguyen AT, Viboud C, Santillana M. Toward the use of neural networks for influenza prediction at multiple spatial resolutions. Science advances 2021.

McGough SF, Clemente L, Kutz JN, Santillana M. A dynamic, ensemble learning approach to forecast dengue fever epidemic years in Brazil using weather and population susceptibility cycles. Journal of the Royal Society, Interface 2021.

Perlis RH, Santillana M, Ognyanova K, Green J, Druckman J, Lazer D, Baum MA. Factors Associated With Self-reported Symptoms of Depression Among Adults With and Without a Previous COVID-19 Diagnosis. JAMA network open 2021.

Bourgeois FT, Gutiérrez-Sacristán A, Keller MS, Liu M, Hong C, Bonzel CL, Tan ALM, Aronow BJ, Boeker M, Booth J, Cruz Rojo J, Devkota B, García Barrio N, Gehlenborg N, Geva A, Hanauer DA, Hutch MR, Issitt RW, Klann JG, Luo Y, Mandl KD, Mao C, Moal B, Moshal KL, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Patel LP, Jiménez MP, Sebire NJ, Balazote PS, Serret-Larmande A, South AM, Spiridou A, Taylor DM, Tippmann P, Visweswaran S, Weber GM, Kohane IS, Cai T, Avillach P, . International Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries. JAMA network open 2021.

Arfè A, Silverman LB, Bourgeois F. Master Protocols and Adaptive Trial Designs to Develop Tumor-Agnostic Drugs for Children: Essential Tools in the Era of the Research to Accelerate Cure and Equity Act. JAMA oncology 2021.

Mandl KD, Perakslis ED. HIPAA and the Leak of "Deidentified" EHR Data. The New England journal of medicine 2021.

Ong MS, Ringold S, Kimura Y, Schanberg LE, Tomlinson GA, Natter MD, . Improved disease course associated with early initiation of biologics in untreated polyarticular Juvenile Idiopathic Arthritis: A trajectory analysis of the STOP-JIA study. Arthritis & rheumatology (Hoboken, N.J.) 2021.

Toomey V, Randolph A, Bourgeois F, Graham D. Variation in Intravenous Acetaminophen Use in Pediatric Hospitals: Priorities for Standardization. Hospital pediatrics 2021.

Feroe AG, Uppal N, Gutiérrez-Sacristán A, Mousavi S, Greenspun P, Surati R, Kohane IS, Avillach P. Medication Use in the Management of Comorbidities Among Individuals With Autism Spectrum Disorder From a Large Nationwide Insurance Database. JAMA pediatrics 2021.

Liu Y, Wang Z, Rader B, Li B, Wu CH, Whittington JD, Zheng P, Stenseth NC, Bjornstad ON, Brownstein JS, Tian H. Associations between changes in population mobility in response to the COVID-19 pandemic and socioeconomic factors at the city level in China and country level worldwide: a retrospective, observational study. The Lancet. Digital health 2021.

He S, Pereira D, David Perez J, Gollub RL, Murphy SN, Prabhu S, Pienaar R, Robertson RL, Ellen Grant P, Ou Y. Multi-channel attention-fusion neural network for brain age estimation: Accuracy, generality, and interpretation with 16,705 healthy MRIs across lifespan. Medical image analysis 2021.

Fabbri A, Nejstgaard CH, Grundy Q, Bero L, Dunn AG, Mohammad A, Mintzes B. Association Between Conflicts of Interest and Authors' Positions on Harms of Varenicline: a Cross-Sectional Analysis. Journal of general internal medicine 2021.

Prince RD, Akhondi-Asl A, Mehta NM, Geva A. A Machine Learning Classifier Improves Mortality Prediction Compared With Pediatric Logistic Organ Dysfunction-2 Score: Model Development and Validation. Critical care explorations 2021.

Miller T, Geva A, Dligach D. Extracting Adverse Drug Event Information with Minimal Engineering. Proceedings of the conference. Association for Computational Linguistics. North American Chapter. Meeting 2019.

Castro LA, Generous N, Luo W, Pastore Y Piontti A, Martinez K, Gomes MFC, Osthus D, Fairchild G, Ziemann A, Vespignani A, Santillana M, Manore CA, Del Valle SY. Using heterogeneous data to identify signatures of dengue outbreaks at fine spatio-temporal scales across Brazil. PLoS neglected tropical diseases 2021.

Lee IH, Lin Y, Alvarez WJ, Hernandez-Ferrer C, Mandl KD, Kong SW. WEScover: selection between clinical whole exome sequencing and gene panel testing. BMC bioinformatics 2021.

Diossy M, Sztupinszki Z, Krzystanek M, Borcsok J, Eklund AC, Csabai I, Pedersen AG, Szallasi Z. Strand Orientation Bias Detector to determine the probability of FFPE sequencing artifacts. Briefings in bioinformatics 2021.

Barak-Corren Y, Agarwal I, Michelson KA, Lyons TW, Neuman MI, Lipsett SC, Kimia AA, Eisenberg MA, Capraro AJ, Levy JA, Hudgins JD, Reis BY, Fine AM. Prediction of patient disposition: comparison of computer and human approaches and a proposed synthesis. Journal of the American Medical Informatics Association : JAMIA 2021.

Poirier C, Hswen Y, Bouzillé G, Cuggia M, Lavenu A, Brownstein JS, Brewer T, Santillana M. Influenza forecasting for French regions combining EHR, web and climatic data sources with a machine learning ensemble approach. PloS one 2021.

Yates J, Gutiérrez-Sacristán A, Jouhet V, LeBlanc K, Esteves C, DeSain TN, Benik N, Stedman J, Palmer N, Mellon G, Kohane I, Avillach P. Finding commonalities in rare diseases through the undiagnosed diseases network. Journal of the American Medical Informatics Association : JAMIA 2021.

Yuan W, Beaulieu-Jones B, Krolewski R, Palmer N, Veyrat-Follet C, Frau F, Cohen C, Bozzi S, Cogswell M, Kumar D, Coulouvrat C, Leroy B, Fischer TZ, Sardi SP, Chandross KJ, Rubin LL, Wills AM, Kohane I, Lipnick SL. Accelerating diagnosis of Parkinson's disease through risk prediction. BMC neurology 2021.

Diao JA, Powe NR, Manrai AK. Removing Race From Kidney Function Estimates-Reply. JAMA 2021.

Kreps S, Dasgupta N, Brownstein JS, Hswen Y, Kriner DL. Public attitudes toward COVID-19 vaccination: The role of vaccine attributes, incentives, and misinformation. NPJ vaccines 2021.

Freilikhman S, Halasi M, Eran A, Adini I. Melanocytes determine angiogenesis gene expression across human tissues. PloS one 2021.

Geisler BP, Zahabi L, Lang AE, Eastwood N, Tennant E, Lukic L, Sharon E, Chuang HH, Kang CB, Clayton-Johnson K, Aljaberi A, Yu H, Bui C, Le Mau T, Li WC, Teodorescu D, Hinske LC, Sun DL, Manian FA, Dunn AG. Repurposing existing medications for coronavirus disease 2019: protocol for a rapid and living systematic review. Systematic reviews 2021.

Börcsök J, Diossy M, Sztupinski Z, Prosz A, Tisza V, Spisak S, Rusz O, Stormoen DR, Pappot H, Csabai I, Brunak S, Mouw KW, Szallasi Z. Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2021.

Geva A, Albert BD, Hamilton S, Manning MJ, Barrett MK, Mirchandani D, Harty M, Morgan EC, Kleinman ME, Mehta NM. eSIMPLER: A Dynamic, Electronic Health Record-Integrated Checklist for Clinical Decision Support During PICU Daily Rounds. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2021.

Li J, Tiwari A, Mirzakhani H, Wang AL, Kho AT, McGeachie MJ, Litonjua AA, Weiss ST, Tantisira KG. Circulating MicroRNA: Incident Asthma Prediction and Vitamin D Effect Modification. Journal of personalized medicine 2021.

Larsen RJ, Gagoski B, Morton SU, Ou Y, Vyas R, Litt J, Grant PE, Sutton BP. Quantification of magnetic resonance spectroscopy data using a combined reference: Application in typically developing infants. NMR in biomedicine 2021.

Goldfarb JL, Kreps S, Brownstein JS, Kriner DL. Beyond the First Dose - Covid-19 Vaccine Follow-through and Continued Protective Measures. The New England journal of medicine 2021.

Liu D, Dligach D, Miller T. Two-stage Federated Phenotyping and Patient Representation Learning. Proceedings of the conference. Association for Computational Linguistics. Meeting 2019.

Mena GE, Martinez PP, Mahmud AS, Marquet PA, Buckee CO, Santillana M. Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile. Science (New York, N.Y.) 2021.

Yang Y, Akhondi-Asl A, Geva A, Dwyer D, Stickney C, Kleinman ME, Madden K, Sanderson A, Mehta NM. Implementation of an Analgesia-Sedation Protocol Is Associated With Reduction in Midazolam Usage in the PICU. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2021.

Srivastava A, Bourgeois FT. Evaluation of Publication of Pediatric Drug Trials. JAMA network open 2021.

Beinvogl B, Palmer N, Kohane I, Nurko S. Healthcare spending and utilization for pediatric Irritable Bowel Syndrome in a commercially insured population. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2021.

Manrai AK. Physicians, Probabilities, and Populations-Estimating the Likelihood of Disease for Common Clinical Scenarios. JAMA internal medicine 2021.

Wang AL, Panganiban R, Qiu W, Kho AT, Chupp G, Meyers DA, Bleecker ER, Weiss ST, Lu Q, Tantisira KG. Drug Repurposing to Treat Glucocorticoid Resistance in Asthma. Journal of personalized medicine 2021.

Beaulieu-Jones BK, Yuan W, Brat GA, Beam AL, Weber G, Ruffin M, Kohane IS. Machine learning for patient risk stratification: standing on, or looking over, the shoulders of clinicians? NPJ digital medicine 2021.

Maharaj AS, Parker J, Hopkins JP, Gournis E, Bogoch II, Rader B, Astley CM, Ivers N, Hawkins JB, VanStone N, Tuite AR, Fisman DN, Brownstein JS, Lapointe-Shaw L. The effect of seasonal respiratory virus transmission on syndromic surveillance for COVID-19 in Ontario, Canada. The Lancet. Infectious diseases 2021.

El Halabi J, Palmer N, McDuffie M, Golub JJ, Fox K, Kohane I, Farhat MR. Measuring health-care delays among privately insured patients with tuberculosis in the USA: an observational cohort study. The Lancet. Infectious diseases 2021.

Molteni E, Astley CM, Ma W, Sudre CH, Magee LA, Murray B, Fall T, Gomez MF, Tsereteli N, Franks PW, Brownstein JS, Davies R, Wolf J, Spector TD, Ourselin S, Steves CJ, Chan AT, Modat M. Symptoms and syndromes associated with SARS-CoV-2 infection and severity in pregnant women from two community cohorts. Scientific reports 2021.

Lindgaard SC, Sztupinszki Z, Maag E, Chen IM, Johansen AZ, Jensen BV, Bojesen SE, Nielsen DL, Hansen CP, Hasselby JP, Nielsen KR, Szallasi Z, Johansen JS. Circulating Protein Biomarkers for Use in Pancreatic Ductal Adenocarcinoma Identification. Clinical cancer research : an official journal of the American Association for Cancer Research 2021.

Ross EL, Zuromski KL, Reis BY, Nock MK, Kessler RC, Smoller JW. Accuracy Requirements for Cost-effective Suicide Risk Prediction Among Primary Care Patients in the US. JAMA psychiatry 2021.

Li J, Hojlo MA, Chennuri S, Gujral N, Paterson HL, Shefchek KA, Genetti CA, Cohn EL, Sewalk KC, Garvey EA, Buttermore ED, Anderson NC, Beggs AH, Agrawal PB, Brownstein JS, Haendel MA, Holm IA, Gonzalez-Heydrich J, Brownstein CA. Underrepresentation of Phenotypic Variability of 16p13.11 Microduplication Syndrome Assessed With an Online Self-Phenotyping Tool (Phenotypr): Cohort Study. Journal of medical Internet research 2021.

Marostica E, Barber R, Denize T, Kohane IS, Signoretti S, Golden JA, Yu KH. Development of a histopathology informatics pipeline for classification and prediction of clinical outcome in subtypes of renal cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 2021.

Gieszer B, Megyesfalvi Z, Dulai V, Papay J, Kovalszky I, Timar J, Fillinger J, Harko T, Pipek O, Teglasi V, Regos E, Papp G, Szallasi Z, Laszlo V, Renyi-Vamos F, Galffy G, Bodor C, Dome B, Moldvay J. EGFR variant allele frequency predicts EGFR-TKI efficacy in lung adenocarcinoma: a multicenter study. Translational lung cancer research 2021.

Wang H, Avillach P. Autism Spectrum Disorders Classification using Genotype Data: A Deep Learning-based Predictive Classifier. JMIR medical informatics 2021.

Perlis RH, Ognyanova K, Santillana M, Baum MA, Lazer D, Druckman J, Della Volpe J. Association of Acute Symptoms of COVID-19 and Symptoms of Depression in Adults. JAMA network open 2021.

Finlayson SG, McDermott MBA, Pickering AV, Lipnick SL, Kohane IS. Cross-modal representation alignment of molecular structure and perturbation-induced transcriptional profiles. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2021.

Jones J, Gottlieb D, Mandel JC, Ignatov V, Ellis A, Kubick W, Mandl KD. A landscape survey of planned SMART/HL7 bulk FHIR data access API implementations and tools. Journal of the American Medical Informatics Association : JAMIA 2021.

Pho N, Manrai AK, Leppert JT, Chertow GM, Ioannidis JPA, Patel CJ. Association of 152 Biomarker Reference Intervals with All-Cause Mortality in Participants of a General United States Survey from 1999 to 2010. Clinical chemistry 2021.

Kogan NE, Clemente L, Liautaud P, Kaashoek J, Link NB, Nguyen AT, Lu FS, Huybers P, Resch B, Havas C, Petutschnig A, Davis J, Chinazzi M, Mustafa B, Hanage WP, Vespignani A, Santillana M. An early warning approach to monitor COVID-19 activity with multiple digital traces in near real time. Science advances 2021.

Deshpande SJ, Vitali S, Thiagarajan R, Brediger S, McManus M, Geva A. Coagulations Studies Do Not Correlate With Each Other or With Hematologic Complications During Pediatric Extracorporeal Membrane Oxygenation. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2021.

Le TT, Gutiérrez-Sacristán A, Son J, Hong C, South AM, Beaulieu-Jones BK, Loh NHW, Luo Y, Morris M, Ngiam KY, Patel LP, Samayamuthu MJ, Schriver E, Tan AL, Moore J, Cai T, Omenn GS, Avillach P, Kohane IS, Visweswaran S, Mowery DL, Xia Z. Multinational Prevalence of Neurological Phenotypes in Patients Hospitalized with COVID-19. medRxiv : the preprint server for health sciences 2021.

Dasgupta N, Lazard A, Brownstein JS. Covid-19 vaccine apps should deliver more to patients. The Lancet. Digital health 2021.

Zhang J, Lai PMR, Can A, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R. Tobacco use and age are associated with different morphologic features of anterior communicating artery aneurysms. Scientific reports 2021.

Morales A, Ing A, Antolik C, Austin-Tse C, Baudhuin LM, Bronicki L, Cirino A, Hawley MH, Fietz M, Garcia J, Ho C, Ingles J, Jarinova O, Johnston T, Kelly MA, Kurtz CL, Lebo M, Macaya D, Mahanta L, Maleszewski J, Manrai AK, Murray M, Richard G, Semsarian C, Thomson KL, Winder T, Ware JS, Hershberger RE, Funke BH, Vatta M, . Harmonizing the Collection of Clinical Data on Genetic Testing Requisition Forms to Enhance Variant Interpretation in Hypertrophic Cardiomyopathy (HCM): A Study from the ClinGen Cardiomyopathy Variant Curation Expert Panel. The Journal of molecular diagnostics : JMD 2021.

Amiri H, Kohane IS, . Machine Learning of Patient Characteristics to Predict Admission Outcomes in the Undiagnosed Diseases Network. JAMA network open 2021.

Kohane IS, Aronow BJ, Avillach P, Beaulieu-Jones BK, Bellazzi R, Bradford RL, Brat GA, Cannataro M, Cimino JJ, García-Barrio N, Gehlenborg N, Ghassemi M, Gutiérrez-Sacristán A, Hanauer DA, Holmes JH, Hong C, Klann JG, Loh NHW, Luo Y, Mandl KD, Mohamad D, Moore JH, Murphy SN, Neuraz A, Ngiam KY, Omenn GS, Palmer N, Patel LP, Pedrera-Jiménez M, Sliz P, South AM, Tan ALM, Taylor DM, Taylor BW, Torti C, Vallejos AK, Wagholikar KB, Weber GM, Cai T. What Every Reader Should Know About Studies Using Electronic Health Record Data but May be Afraid to Ask. Journal of medical Internet research 2021.

Cutillo CM, Sharma KR, Foschini L, Kundu S, Mackintosh M, Mandl KD, . Machine intelligence in healthcare-perspectives on trustworthiness, explainability, usability, and transparency. NPJ digital medicine 2020.

Brat GA, Weber GM, Gehlenborg N, Avillach P, Palmer NP, Chiovato L, Cimino J, Waitman LR, Omenn GS, Malovini A, Moore JH, Beaulieu-Jones BK, Tibollo V, Murphy SN, Yi SL, Keller MS, Bellazzi R, Hanauer DA, Serret-Larmande A, Gutierrez-Sacristan A, Holmes JJ, Bell DS, Mandl KD, Follett RW, Klann JG, Murad DA, Scudeller L, Bucalo M, Kirchoff K, Craig J, Obeid J, Jouhet V, Griffier R, Cossin S, Moal B, Patel LP, Bellasi A, Prokosch HU, Kraska D, Sliz P, Tan ALM, Ngiam KY, Zambelli A, Mowery DL, Schiver E, Devkota B, Bradford RL, Daniar M, Daniel C, Benoit V, Bey R, Paris N, Serre P, Orlova N, Dubiel J, Hilka M, Jannot AS, Breant S, Leblanc J, Griffon N, Burgun A, Bernaux M, Sandrin A, Salamanca E, Cormont S, Ganslandt T, Gradinger T, Champ J, Boeker M, Martel P, Esteve L, Gramfort A, Grisel O, Leprovost D, Moreau T, Varoquaux G, Vie JJ, Wassermann D, Mensch A, Caucheteux C, Haverkamp C, Lemaitre G, Bosari S, Krantz ID, South A, Cai T, Kohane IS. International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium. NPJ digital medicine 2020.

Yuan W, Beaulieu-Jones BK, Yu KH, Lipnick SL, Palmer N, Loscalzo J, Cai T, Kohane IS. Temporal bias in case-control design: preventing reliable predictions of the future. Nature communications 2021.

Lee JW, Lee IH, Sato T, Kong SW, Iimura T. Genetic variation analyses indicate conserved SARS-CoV-2-host interaction and varied genetic adaptation in immune-response factors in modern human evolution. Development, growth & differentiation 2021.

Geva A, Liu M, Panickan VA, Avillach P, Cai T, Mandl KD. A high-throughput phenotyping algorithm is portable from adult to pediatric populations. Journal of the American Medical Informatics Association : JAMIA 2021.

Inan OT, Tenaerts P, Prindiville SA, Reynolds HR, Dizon DS, Cooper-Arnold K, Turakhia M, Pletcher MJ, Preston KL, Krumholz HM, Marlin BM, Mandl KD, Klasnja P, Spring B, Iturriaga E, Campo R, Desvigne-Nickens P, Rosenberg Y, Steinhubl SR, Califf RM. Digitizing clinical trials. NPJ digital medicine 2020.

Kobren SN, Baldridge D, Velinder M, Krier JB, LeBlanc K, Esteves C, Pusey BN, Züchner S, Blue E, Lee H, Huang A, Bastarache L, Bican A, Cogan J, Marwaha S, Alkelai A, Murdock DR, Liu P, Wegner DJ, Paul AJ, , Sunyaev SR, Kohane IS. Commonalities across computational workflows for uncovering explanatory variants in undiagnosed cases. Genetics in medicine : official journal of the American College of Medical Genetics 2021.

Alterovitz G, Heale B, Jones J, Kreda D, Lin F, Liu L, Liu X, Mandl KD, Poloway DW, Ramoni R, Wagner A, Warner JL. FHIR Genomics: enabling standardization for precision medicine use cases. NPJ genomic medicine 2020.

Lu T, Reis BY. Internet search patterns reveal clinical course of COVID-19 disease progression and pandemic spread across 32 countries. NPJ digital medicine 2021.

Lee JW, Lee IH, Iimura T, Kong SW. Two macrophages, osteoclasts and microglia: from development to pleiotropy. Bone research 2021.

Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Morris M, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Samayamuthu MJ, Xia Z, Hutch M, Luo Y, , Kohane IS, Brat GA, Murphy SN. Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data. Journal of the American Medical Informatics Association : JAMIA 2021.

Weber GM, Hong C, Palmer NP, Avillach P, Murphy SN, Gutiérrez-Sacristán A, Xia Z, Serret-Larmande A, Neuraz A, Omenn GS, Visweswaran S, Klann JG, South AM, Loh NHW, Cannataro M, Beaulieu-Jones BK, Bellazzi R, Agapito G, Alessiani M, Aronow BJ, Bell DS, Bellasi A, Benoit V, Beraghi M, Boeker M, Booth J, Bosari S, Bourgeois FT, Brown NW, Bucalo M, Chiovato L, Chiudinelli L, Dagliati A, Devkota B, DuVall SL, Follett RW, Ganslandt T, García Barrio N, Gradinger T, Griffier R, Hanauer DA, Holmes JH, Horki P, Huling KM, Issitt RW, Jouhet V, Keller MS, Kraska D, Liu M, Luo Y, Lynch KE, Malovini A, Mandl KD, Mao C, Maram A, Matheny ME, Maulhardt T, Mazzitelli M, Milano M, Moore JH, Morris JS, Morris M, Mowery DL, Naughton TP, Ngiam KY, Norman JB, Patel LP, Pedrera Jimenez M, Ramoni RB, Schriver ER, Scudeller L, Sebire NJ, Serrano Balazote P, Spiridou A, Tan AL, Tan BWL, Tibollo V, Torti C, Trecarichi EM, Vitacca M, Zambelli A, Zucco C, Kohane IS, Cai T, Brat GA. International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort Study. medRxiv : the preprint server for health sciences 2021.

He Y, Lakhani CM, Rasooly D, Manrai AK, Tzoulaki I, Patel CJ. Comparisons of Polyexposure, Polygenic, and Clinical Risk Scores in Risk Prediction of Type 2 Diabetes. Diabetes care 2021.

Gooding HC, Gauvreau K, Bachman J, Baker A, Griggs SS, Hartz J, Huang Y, Mendelson MM, Palfrey H, de Ferranti SD. Improving Cardiovascular Health in a Pediatric Preventive Cardiology Practice. The Journal of pediatrics 2021.

Levin JC, Beam AL, Fox KP, Mandl KD. Medication utilization in children born preterm in the first two years of life. Journal of perinatology : official journal of the California Perinatal Association 2021.

Bitterman DS, Miller TA, Mak RH, Savova GK. Clinical natural language processing for radiation oncology: A review and practical primer. International journal of radiation oncology, biology, physics 2021.

Kossowsky J, Magane KM, Levy S, Weitzman ER. Marijuana Use to Address Symptoms and Side Effects by Youth With Chronic Medical Conditions. Pediatrics 2021.

Sadilek A, Hswen Y, Bavadekar S, Shekel T, Brownstein JS, Gabrilovich E. Lymelight: forecasting Lyme disease risk using web search data. NPJ digital medicine 2020.

Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R. Morphological variables associated with ruptured basilar tip aneurysms. Scientific reports 2021.

Sztupinszki Z, Le Naour J, Vacchelli E, Laurent-Puig P, Delaloge S, Szallasi Z, Kroemer G. A major genetic accelerator of cancer diagnosis: rs867228 in FPR1. Oncoimmunology 2021.

Rader B, White LF, Burns MR, Chen J, Brilliant J, Cohen J, Shaman J, Brilliant L, Kraemer MUG, Hawkins JB, Scarpino SV, Astley CM, Brownstein JS. Mask-wearing and control of SARS-CoV-2 transmission in the USA: a cross-sectional study. The Lancet. Digital health 2021.

Sayeed R, Gottlieb D, Mandl KD. SMART Markers: collecting patient-generated health data as a standardized property of health information technology. NPJ digital medicine 2020.

Cramer AK, Plana D, Yang H, Carmack MM, Tian E, Sinha MS, Krikorian D, Turner D, Mo J, Li J, Gupta R, Manning H, Bourgeois FT, Yu SH, Sorger PK, LeBoeuf NR. Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE. Scientific reports 2021.

Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer V, Shadick N, Savova G, Murphy SN, Cai T, Weiss ST, Du R. Geometric variations associated with posterior communicating artery aneurysms. Journal of neurointerventional surgery 2021.

Kiang MV, Santillana M, Chen JT, Onnela JP, Krieger N, Engø-Monsen K, Ekapirat N, Areechokchai D, Prempree P, Maude RJ, Buckee CO. Incorporating human mobility data improves forecasts of Dengue fever in Thailand. Scientific reports 2021.

Rubinstein YR, Robinson PN, Gahl WA, Avillach P, Baynam G, Cederroth H, Goodwin RM, Groft SC, Hansson MG, Harris NL, Huser V, Mascalzoni D, McMurry JA, Might M, Nellaker C, Mons B, Paltoo DN, Pevsner J, Posada M, Rockett-Frase AP, Roos M, Rubinstein TB, Taruscio D, van Enckevort E, Haendel MA. The case for open science: rare diseases. JAMIA open 2020.

Ferenczi S, Solymosi N, Horváth I, Szeőcs N, Grózer Z, Kuti D, Juhász B, Winkler Z, Pankotai T, Sükösd F, Stágel A, Paholcsek M, Dóra D, Nagy N, Kovács KJ, Zanoni I, Szallasi Z. Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria. Molecular therapy. Methods & clinical development 2021.

Liu D, Olson KL, Manzi SF, Mandl KD. Patients dispensed medications with actionable pharmacogenomic biomarkers: rates and characteristics. Genetics in medicine : official journal of the American College of Medical Genetics 2021.

Diao JA, Inker LA, Levey AS, Tighiouart H, Powe NR, Manrai AK. In Search of a Better Equation - Performance and Equity in Estimates of Kidney Function. The New England journal of medicine 2021.

McGraw, D., Mandl, K.D. Privacy protections to encourage use of health-relevant digital data in a learning health system. npj Digital Medicine 2021.

Si Y, Du J, Li Z, Jiang X, Miller T, Wang F, Jim Zheng W, Roberts K. Deep Representation Learning of Patient Data from Electronic Health Records (EHR): A Systematic Review. Journal of biomedical informatics 2020.

Tiwari A, Li J, Kho AT, Sun M, Lu Q, Weiss ST, Tantisira KG, McGeachie MJ. COPD-Associated miR-145-5p is Downregulated in Early Decline FEV1 Trajectories in Childhood Asthma. The Journal of allergy and clinical immunology 2020.

Lam BD, Bourgeois F, Dong ZJ, Bell SK. Speaking up about patient-perceived serious visit note errors: Patient and family experiences and recommendations. Journal of the American Medical Informatics Association : JAMIA 2020.

Sudre CH, Keshet A, Graham MS, Joshi AD, Shilo S, Rossman H, Murray B, Molteni E, Klaser K, Canas LS, Antonelli M, Modat M, Capdevila Pujol J, Ganesh S, Wolf J, Meir T, Chan AT, Steves C, Spector T, Brownstein JS, Segal E, Ourselin S, Astley C. Anosmia and other SARS-CoV-2 positive test-associated symptoms, across three national, digital surveillance platforms as the COVID-19 pandemic and response unfolded: an observation study. medRxiv : the preprint server for health sciences 2020.

Bashir R, Dunn AG, Surian D. A rule-based approach for automatically extracting data from systematic reviews and their updates to model the risk of conclusion change. Research synthesis methods 2020.

Viboud C, Santillana M. Fitbit-informed influenza forecasts. The Lancet. Digital health 2020.

Patel BB, Sperotto F, Molina M, Kimura S, Delgado MI, Santillana M, Kheir JN. Avoidable Serum Potassium Testing in the Cardiac ICU: Development and Testing of a Machine-Learning Model. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2020.

Ding X, Hall MH, Miller TA. Incorporating Risk Factor Embeddings in Pre-trained Transformers Improves Sentiment Prediction in Psychiatric Discharge Summaries. Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing 2020.

Merz AA, Gutiérrez-Sacristán A, Bartz D, Williams NE, Ojo A, Schaefer KM, Huang M, Li CY, Sofia Sandoval R, Ye S, Cathcart AM, Starosta A, Avillach P. Population attitudes toward contraceptive methods over time on a social media platform.American journal of obstetrics and gynecology 2020.

Zhang J, Can A, Rosalind Lai PM, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R. Vascular geometry associated with anterior communicating artery aneurysm formation. World neurosurgery 2020.

Sayeed R, Jones J, Gottlieb D, Mandel JC, Mandl KD. A proposal for shoring up Federal Trade Commission protections for electronic health record-connected consumer apps under 21st Century Cures.Journal of the American Medical Informatics Association : JAMIA 2020.

Gordon WJ, Mandl KD. The 21st Century Cures Act: A Competitive Apps Market and the Risk of Innovation Blocking. Journal of medical Internet research 2020.

Hswen Y, Brownstein JS, Xu X, Yom-Tov E. Early detection of COVID-19 in China and the USA: summary of the implementation of a digital decision-support and disease surveillance tool. BMJ open 2020.

Brownstein JS, Nahari AD, Reis BY. Internet search patterns reveal firearm sales, policies, and deaths. NPJ digital medicine 2020.

Mandl KD, Gottlieb D, Mandel JC, Ignatov V, Sayeed R, Grieve G, Jones J, Ellis A, Culbertson A. Push Button Population Health: The SMART/HL7 FHIR Bulk Data Access Application Programming Interface. NPJ digital medicine 2020.

Sharma S, Kho AT, Chhabra D, Haley K, Vyhlidal C, Gaedigk R, Leeder JS, Tantisira KG, Raby B, Weiss ST. Effect of Intrauterine Smoke Exposure on microRNA-15a Expression in Human Lung Development and Subsequent Asthma Risk. Healthcare (Basel, Switzerland) 2020.

Sotardi S, Gollub RL, Bates SV, Weiss R, Murphy SN, Grant PE, Ou Y. Voxelwise and Regional Brain Apparent Diffusion Coefficient Changes on MRI from Birth to 6 Years of Age. Radiology 2020.

Miron O, Yu KH, Wilf-Miron R, Kohane I, Davidovitch N. COVID-19 infections following physical school reopening. Archives of disease in childhood 2020.

Diao JA, Wu GJ, Taylor HA, Tucker JK, Powe NR, Kohane IS, Manrai AK. Clinical Implications of Removing Race From Estimates of Kidney Function. JAMA 2020.

Madhavan S, Bastarache L, Brown JS, Butte AJ, Dorr DA, Embi PJ, Friedman CP, Johnson KB, Moore JH, Kohane IS, Payne PRO, Tenenbaum JD, Weiner MG, Wilcox AB, Ohno-Machado L. Use of electronic health records to support a public health response to the COVID-19 pandemic in the United States: a perspective from 15 academic medical centers. Journal of the American Medical Informatics Association : JAMIA 2020.

Dligach D, Afshar M, Miller T. Pre-training phenotyping classifiers. Journal of biomedical informatics 2020.

Amin S, Dunn AG, Laranjo L. Why do people start or stop using e-cigarettes in Australia? A qualitative interview-based study. Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals 2020.

Geva A, Stedman JP, Manzi SF, Lin C, Savova GK, Avillach P, Mandl KD. Adverse drug event presentation and tracking (ADEPT): semiautomated, high throughput pharmacovigilance using real-world data. JAMIA open 2020.

Börcsök J, Sztupinszki Z, Bekele R, Gao SP, Diossy M, Samant AS, Dillon KM, Tisza V, Spisák S, Rusz O, Csabai I, Pappot H, Frazier ZJ, Konieczkowski DJ, Liu D, Vasani N, Rodrigues JA, Solit DB, Hoffman-Censits JH, Plimack ER, Rosenberg JE, Lazaro JB, Taplin ME, Iyer G, Brunak S, Lozsa R, Van Allen EM, Szüts D, Mouw KW, Szallasi Z. Identification of a synthetic lethal relationship between nucleotide excision repair (NER) deficiency and irofulven sensitivity in urothelial cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2020.

Gokuldass A, Draghi A, Papp K, Borch TH, Nielsen M, Westergaard MCW, Andersen R, Schina A, Bol KF, Chamberlain CA, Presti M, Met Ö, Harbst K, Lauss M, Soraggi S, Csabai I, Szállási Z, Jönsson G, Svane IM, Donia M. Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8 T Cells in Non-Melanoma Cancers Compared to Melanoma. Cancers 2020.

Perera G, Rijnbeek PR, Alexander M, Ansell D, Avillach P, Duarte-Salles T, Gordon MF, Lapi F, Mayer MA, Pasqua A, Pedersen L, van Der Lei J, Visser PJ, Stewart R. Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case-control study using European electronic health records. BMJ open 2020.

Xie F, Dai S, Zhao Y, Huang P, Yu S, Ren B, Wang Q, Ji Z, Alterovitz G, Zhang Q, Zhang J, Chen X, Jiang L, Song F, Liu H, Ausubel FM, Liu X, Dai H, Zhang L. Generation of Fluorinated Amychelin Siderophores against Pseudomonas aeruginosa Infections by a Combination of Genome Mining and Mutasynthesis. Cell chemical biology 2020.

McGough SF, MacFadden DR, Hattab MW, Mølbak K, Santillana M. Rates of increase of antibiotic resistance and ambient temperature in Europe: a cross-national analysis of 28 countries between 2000 and 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2020.

Bourgeois FT, Avillach P, Turner MA. The urgent need for research coordination to advance knowledge on COVID-19 in children. Pediatric research 2020.

Gendron TF, Badi MK, Heckman MG, Jansen-West KR, Vilanilam GK, Johnson PW, Burch AR, Walton RL, Ross OA, Brott TG, Miller TM, Berry JD, Nicholson KA, Wszolek ZK, Oskarsson BE, Sheth KN, Sansing LH, Falcone GJ, Cucchiara BL, Meschia JF, Petrucelli L. Plasma neurofilament light predicts mortality in patients with stroke. Science translational medicine 2020.

Peters GA, Ordoobadi AJ, Cash RE, Wong ML, Avillach P, Camargo CA. Association of Affordable Care Act Implementation With Ambulance Utilization for Asthma Emergencies in New York City, 2008-2018. JAMA network open 2020.

Saini SK, Ørskov AD, Bjerregaard AM, Unnikrishnan A, Holmberg-Thydén S, Borch A, Jensen KV, Anande G, Bentzen AK, Marquard AM, Tamhane T, Treppendahl MB, Gang AO, Dufva IH, Szallasi Z, Ternette N, Pedersen AG, Eklund AC, Pimanda J, Grønbæk K, Hadrup SR. Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers. Nature communications 2020.

Bourgeois F, Doshi P, Hong K, Jefferson T, Jones M, Lee H, Rowhani-Farid A, Shamseer L, Spence O. Incompletely Reported Important Methodological Details and Inaccurate Description of the Formulation That the Control Arms Received in a Gardasil Vaccine Trial. mSphere 2020.

Miron O, Delgado RE, Delgado CF, Simpson EA, Yu KH, Gutierrez A, Zeng G, Gerstenberger JN, Kohane IS. Prolonged Auditory Brainstem Response in Universal Hearing Screening of Newborns with Autism Spectrum Disorder. Autism research : official journal of the International Society for Autism Research 2020.

Hswen Y, Zhang A, Sewalk KC, Tuli G, Brownstein JS, Hawkins JB. Investigation of Geographic and Macrolevel Variations in LGBTQ Patient Experiences: Longitudinal Social Media Analysis. Journal of medical Internet research 2020.

Hanage WP, Testa C, Chen JT, Davis L, Pechter E, Seminario P, Santillana M, Krieger N. COVID-19: US federal accountability for entry, spread, and inequities-lessons for the future. European journal of epidemiology 2020.

, Feigin VL, Vos T, Alahdab F, Amit AML, Bärnighausen TW, Beghi E, Beheshti M, Chavan PP, Criqui MH, Desai R, Dhamminda Dharmaratne S, Dorsey ER, Wilder Eagan A, Elgendy IY, Filip I, Giampaoli S, Giussani G, Hafezi-Nejad N, Hole MK, Ikeda T, Owens Johnson C, Kalani R, Khatab K, Khubchandani J, Kim D, Koroshetz WJ, Krishnamoorthy V, Krishnamurthi RV, Liu X, Lo WD, Logroscino G, Mensah GA, Miller TR, Mohammed S, Mokdad AH, Moradi-Lakeh M, Morrison SD, Shivamurthy VKN, Naghavi M, Nichols E, Norrving B, Odell CM, Pupillo E, Radfar A, Roth GA, Shafieesabet A, Sheikh A, Sheikhbahaei S, Shin JI, Singh JA, Steiner TJ, Stovner LJ, Wallin MT, Weiss J, Wu C, Zunt JR, Adelson JD, Murray CJL. Burden of Neurological Disorders Across the US From 1990-2017: A Global Burden of Disease Study. JAMA neurology 2020.

Sun JW, Bourgeois FT, Haneuse S, Hernández-Díaz S, Landon JE, Bateman BT, Huybrechts KF. Development and Validation of a Pediatric Comorbidity Index. American journal of epidemiology 2020.

Sun JW, Hernández-Díaz S, Bourgeois FT, Haneuse S, Brill G, Bateman BT, Huybrechts KF. Antidiabetic Medication Use in Commercially-Insured Children and Adolescents in the United States from 2004 to 2019. Diabetes, obesity & metabolism 2020.

Nam K, Larholt K, Hirsch G, Beninger P, Fritsche D, Shoda D, Ferguson J, Bourgeois FT, Palmer D, Katz K, Courtney MW. Dynamic Dossier in the Cloud: A Sociotechnical Architecture for a Real-Time and Metrics-Based Data Tracking System with Gene and Cell Therapies as a Case Study. Therapeutic innovation & regulatory science 2020.

Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R. Surrounding vascular geometry associated with basilar tip aneurysm formation. Scientific reports 2020.

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Poirier C, Luo W, Majumder MS, Liu D, Mandl KD, Mooring TA, Santillana M. The role of environmental factors on transmission rates of the COVID-19 outbreak: an initial assessment in two spatial scales. Scientific reports 2020.

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Kho AT, Sordillo J, Wu AC, Cho MH, Sharma S, Tiwari A, Lasky-Su J, Weiss ST, Tantisira KG, McGeachie MJ. CASTER: Cross-Sectional Asthma STEroid Response Measurement. Journal of personalized medicine 2020.

Valcz G, Buzás EI, Sebestyén A, Krenács T, Szállási Z, Igaz P, Molnár B. Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy. Cancers 2020.

Inan OT, Tenaerts P, Prindiville SA, Reynolds HR, Dizon DS, Cooper-Arnold K, Turakhia M, Pletcher MJ, Preston KL, Krumholz HM, Marlin BM, Mandl KD, Klasnja P, Spring B, Iturriaga E, Campo R, Desvigne-Nickens P, Rosenberg Y, Steinhubl SR, Califf RM. Digitizing clinical trials. NPJ digital medicine 2020.

Hswen Y, Hawkins JB, Sewalk K, Tuli G, Williams DR, Viswanath K, Subramanian SV, Brownstein JS. Racial and Ethnic Disparities in Patient Experiences in the United States: 4-Year Content Analysis of Twitter. Journal of medical Internet research 2020.

Fluckiger A, Daillère R, Sassi M, Sixt BS, Liu P, Loos F, Richard C, Rabu C, Alou MT, Goubet AG, Lemaitre F, Ferrere G, Derosa L, Duong CPM, Messaoudene M, Gagné A, Joubert P, De Sordi L, Debarbieux L, Simon S, Scarlata CM, Ayyoub M, Palermo B, Facciolo F, Boidot R, Wheeler R, Boneca IG, Sztupinszki Z, Papp K, Csabai I, Pasolli E, Segata N, Lopez-Otin C, Szallasi Z, Andre F, Iebba V, Quiniou V, Klatzmann D, Boukhalil J, Khelaifia S, Raoult D, Albiges L, Escudier B, Eggermont A, Mami-Chouaib F, Nistico P, Ghiringhelli F, Routy B, Labarrière N, Cattoir V, Kroemer G, Zitvogel L. Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage. Science (New York, N.Y.) 2020.

Levy S, Weitzman ER, Marin AC, Magane KM, Wisk LE, Shrier LA. Sensitivity and specificity of S2BI for identifying alcohol and cannabis use disorders among adolescents presenting for primary care. Substance abuse 2020.

Yu KH, Hu V, Wang F, Matulonis UA, Mutter GL, Golden JA, Kohane IS. Deciphering serous ovarian carcinoma histopathology and platinum response by convolutional neural networks. BMC medicine 2020.

Dyda A, King C, Dey A, Leask J, Dunn AG. A systematic review of studies that measure parental vaccine attitudes and beliefs in childhood vaccination. BMC public health 2020.

Aiken EL, McGough SF, Majumder MS, Wachtel G, Nguyen AT, Viboud C, Santillana M. Real-time estimation of disease activity in emerging outbreaks using internet search information. PLoS computational biology 2020.

Luo Y, Eran A, Palmer N, Avillach P, Levy-Moonshine A, Szolovits P, Kohane IS. A multidimensional precision medicine approach identifies an autism subtype characterized by dyslipidemia. Nature medicine 2020.

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Yu KH, Lee TM, Yen MH, Kou SC, Rosen B, Chiang JH, Kohane IS. Reproducible Machine Learning Methods for Lung Cancer Detection Using Computed Tomography Images: Algorithm Development and Validation. Journal of medical Internet research 2020.

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Miller TA, Avillach P, Mandl KD. Experiences implementing scalable, containerized, cloud-based NLP for extracting biobank participant phenotypes at scale. JAMIA open 2020.

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